Image Analysis Scientist III
South San Francisco, CA (can be hybrid/remote)
1 yr. initial contract
Hourly Pay Rate: $65-68/hr (for hybrid/onsite worker), $60-63/hr (for fully remote worker)
Orion Group is seeking a skilled Imaging Scientist for our global pharmaceutical client in South San Francisco, CA. This position is open to either an onsite/hybrid worker or fully remote from anywhere in the US.
This Scientist will work within the Precision Medicine Pathology team. This team drives the scientific strategy for translational tissue-based biomarker development & discovery target validation/MOA projects, leads pathology collaborative programs, conducts histopathological evaluation & analysis of IHC & spatial biology technologies, and provides technical/scientific leadership to histotechnicians & pathology scientists.
The successful candidate will have advanced knowledge and extended experience in analysis of high-plex images generated on the Akoya PhenoCycler Fusion platform.
Responsibilities:
- Implementation of different scripts and pipelines for analysis of high-plex PhenoCycler Fusion (CODEX) images.
- Independently performing end-to-end high-plex image analysis (tissue classification, cell segmentation, detection of marker positivity, cell phenotyping, unsupervised clustering, neighborhood analysis, proximity analysis).
- Acting as a subject matter resource and training other team members in high-plex image analysis tasks.
- Collaborating with pathologists and digital pathology scientists to support image analysis projects.
- Presenting the results and findings from spatial proteomics studies to stakeholders.
Qualifications:
- MSc, PhD, or equivalent degree in biological sciences/engineering/computer science/informatics
- Fluency in Python and R Studio
- Experience Level = 5-7 Years for BS/MS graduates, and 3-4 years for PhD
- Experience in implementing and utilizing open-source scripts and pipelines for high-plex image analysis
- Experience in quantitative digital pathology analysis platforms such as Halo, Visiopharm, QuPath
- Close familiarity with tissue microscopic anatomy and histology (normal and diseased) is a plus
- Excellent verbal communication skills are required including the demonstrated ability to effectively and clearly summarize results for presentation and report generation
- Strong motivation, attention to detail, ability to think independently and fully integrate into a high achieving team environment
- Ability to multi-task and manage multiple projects
Must Have Skills:
- Ability to run High-plex image analysis pipelines & scripts - must be able to perform end-to-end high-plex image analysis
- Python & R studio experience - must be able to write their own scripts as well as using published ones
Our role in supporting diversity and inclusion
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.
